Expresión de búsqueda:
CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, TYPE 6
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DeCS
Descriptor
Inglés
:
Cyclic Nucleotide Phosphodiesterases, Type 6
Descriptor
Español
:
Fosfodiesterasas de Nucleótidos Cíclicos Tipo 6
Descriptor
Portugués
:
Nucleotídeo Cíclico Fosfodiesterase do Tipo 6
Categoría:
D08.811.277.352.640.150.600
D08.811.277.352.640.155.750
D12.644.360.008.600
D12.644.360.009.750
D12.776.476.008.600
D12.776.476.009.750
Definición
Inglés
:
A cyclic nucleotide phosphodiesterase subfamily that is highly specific for
CYCLIC GMP
. It is found predominantly in the outer segment
PHOTORECEPTOR CELLS
of the
RETINA
. It is comprised of two catalytic subunits, referred to as alpha and beta, that form a dimer. In addition two regulatory subunits, referred to as gamma and
delta
, modulate the activity and localization of the enzyme.
Nota Histórica
Inglés
:
2008(2001)
Calificadores Permitidos
Inglés
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Número del Registro:
52681
Identificador Único:
D054707
Ocurrencia en la BVS
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS